Postdoctoral Research Scientist - Bioinformatician (High-throughput Genomics/Transcriptomics)

All UK vacanciesAcademic or ResearchPostdoctoral Research Scientist - Bioinformatician (High-throughput Genomics/Transcriptomics)

Biological Sciences,Biology,Genetics,Other Biological Sciences,Computer Science,Computer Science,Information Systems

Short info about job

Company: Babraham Institute

Salary: £30,751 to £43,342 per annum (depending on experience)

Hours: Full Time

Contract type: Permanent

Type / Role: Academic or Research

Phone: +44-1569 4778472

Fax: +44-1239 6552490

E-mail: N\A

Site:

Detail information about job Postdoctoral Research Scientist - Bioinformatician (High-throughput Genomics/Transcriptomics). Terms and conditions vacancy

The Babraham Institute is a charity which is world renowned for its research in life sciences to enhance lives and improve wellbeing.

We are looking to recruit a Bioinformatician to join a successful international team studying the mechanisms of gene expression in the immune system.  The laboratory consists of five groups studying various aspects of immunology. 

The post holder will take a lead role in the development of methods to analyse the transcriptome of lymphocytes where available tools do not suffice to address the relevant biological questions. There will be an emphasis on the analysis of the dynamics of gene expression, identification of different mRNA isoforms and the discovery of novel transcripts and open reading frames.  In addition to leading their own project the applicant will assist others with the design and analysis of experiments involving next generation sequencing.

The successful applicant at the higher level will be a PhD level bioinformatician with experience in the design and analysis of experiments that use next generation sequencing to gain information on gene expression mechanisms.  Experience using existing packages for high throughput sequence analysis will be essential and experience in the development of novel analysis tools desirable. 

We will also consider less experienced individuals, with a relevant biological background, who can demonstrate the ability and determination to become skilled in bioinformatics.

Some examples of our work can be found below. For more information on our science please visit our website

  • Rebecca Newman, Helena Ahlfors, Alexander Saveliev, Alison Galloway, Charlotte Cook,Daniel J Hodson, Robert Williams, Adam Cunningham, Sarah E Bell and Martin Turner.  “Maintenance of the marginal zone B cell compartment specifically requires the RNA binding protein ZFP36l1” Nature Immunology June 2017. 18(6):683-693. 
  • Galloway, A., Saveliev, A., Łukasiak, S., Hodson, D.J., Bolland, D., Balmanno, K., Ahlfors, H., Monzón-Casanova, E., Ciullini-Mannurita, S., Bell, L.S., Andrews, S. R., Díaz-Muñoz, M.D., Cook, S. J., Corcoran, A. and Turner M. “RNA binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence". Science 352:453 
  • Diaz-Muñoz,. M. D., Bell, S.E., Fairfax, K., Monzon-Casanova, E., Cunningham, A.F. Gonzalez-Porta, M., Andrews, S.R., Bunik, V. I., Zarnack, K., Curk, T.,  Ward A. Heggermont, W.A., Heymans, S., Gibson, G.E.,. Kontoyiannis, D. L., Ule, J., and TurnerM.  (2015) HuR-dependent regulation of mRNA splicing is essential for the B cell antibody response. Nature Immunology (4):415-25.

This position is available immediately.

Informal enquiries may be made to Dr Martin Turner [email protected]

Further information about the Institute can be found on our website. Application forms and further details are available electronically from our website (www.babraham.ac.uk), or e-mail:  [email protected] 

On applying please quote reference RC-BNF-MT.

Closing date for completed applications Wednesday 13 September 2017. Interviews will take place on Thursday 28 September 2017, Monday 2 October 2017 and Tuesday 3 October 2017.

No agencies please.

The Babraham Institute is a user of the disability symbol and is positive about disabled people.

The Babraham Institute receives strategic funding from the Biotechnology and Biological Sciences Research Council and is an Equal Opportunities Employer.

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