Research Associate

All UK vacanciesAcademic or ResearchResearch Associate

Health and Medical,Anatomy, Physiology and Pathology,Biological Sciences,Biology,Genetics,Microbiology,Molecular Biology and Biophysics

Short info about job

Company: University of Bristol

Department: School of Cellular and Molecular Medicine

Salary: £32,004 to £36,001

Hours: Full Time

Contract type: Fixed-Term/Contract

Type / Role: Academic or Research

Phone: +44-1433 9370758

Fax: +44-1262 3709228

E-mail: N\A

Site:

Detail information about job Research Associate. Terms and conditions vacancy

A postdoctoral Research Associate is required immediately to work on an 18-month project funded by the Little Princess Trust, to investigate the epigenetic deregulation of splicing factors in Wilms' tumour (WT), a common childhood kidney cancer. Molecular and cell biology methods will be used to examine how epigenetic inactivation of the splicing regulator ESRP2 acts as a tumour suppressor in WT by:

  • Identifying target genes whose expression and /or splicing is regulated by ESRP2 in WT cells and kidney cells.
  • Determining the biological effects of ESRP2 in WT cells and kidney cells.
  • The project involves collaboration between members of the Cancer Epigenetics Laboratory in the School of Cellular and Molecular Medicine (Dr Keith Brown and Dr Karim Malik) and with Dr Sebastian Oltean (University of Exeter). This combination will give the candidate access to expertise in technologies covering both epigenetic modifications and cell functional analyses. The project would suit a recently qualified PhD graduate with expertise in mammalian molecular and cell biology.

    Informal enquiries would be welcome to: Dr. Keith Brown ([email protected])

    The closing date for applications is midnight on Sunday 24th September 2017.

    It is anticipated that interviews will take place during the week commencing 23 October 2017.

    The University is committed to creating and sustaining a fully inclusive culture. We welcome applicants from all backgrounds and communities.

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