PhD Studentship: Exploiting DNA Repair Defects with Topoisomerase Poisons and Nucleoside Analogues

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Health and Medical,Anatomy, Physiology and Pathology,Pharmacology, Toxicology and Pharmacy,Biological Sciences,Biology,Genetics,Physical and Environmental Sciences,Chemistry

Short info about job

Company: Bangor University

Department: School of Medical Sciences

Hours: Full Time

Type / Role: PhD

Phone: +44-1223 5654632

Fax: +44-1371 4174499

E-mail: N\A

Site:

Detail information about job PhD Studentship: Exploiting DNA Repair Defects with Topoisomerase Poisons and Nucleoside Analogues. Terms and conditions vacancy

Project Description:

A PhD studentship, jointly funded by a Knowledge Economy Skills Scholarship (KESS 2) and Tenovus, is available as part of a collaboration between Dr. Edgar Hartsuiker, (NWCR Institute, School of Medical Science, Bangor University) and Prof. Andrea Brancale (School of Pharmacy and Pharmaceutical Sciences, Cardiff University). 

The aim of this project is to screen for and develop novel nuclease inhibitors and to explore synthetic lethal interactions between these inhibitors and mutations in, or inhibitors  against other DNA repair pathways involved in cancer drug resistance.

Applicants should have a first, upper second-class or MSc degree (or equivalent EU qualification) in pharmacology, chemistry, biology or a related life-science subject. The application should include a cover letter, CV and two reference letters. The application deadline is 15 September 2017. Successful candidates are expected to commence on or after October 2017. 

The PhD studentship will provide the successful candidate with a stipend (starting at £14,553 per year, tax free) and graduate school fees.

Completed applications should be submitted electronically, or by post, to:  Dr. Edgar Hartsuiker  NWCR Institute  School of Medical Sciences  Brambell Building  Deiniol Road  Bangor LL57 2UW  United Kingdom  e-mail: [email protected]

Knowledge Economy Skills Scholarships (KESS 2) is a pan-Wales higher level skills initiative led by Bangor University on behalf of the HE sector in Wales. It is part funded by the Welsh Government’s European Social Fund (ESF) convergence programme for West Wales and the Valleys.

Due to ESF funding, eligibility restrictions apply to this scholarship. To be eligible, the successful candidate will need to be resident in the Convergence Area of Wales on University registration, and must have the right to work in the region on qualification. 

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