Scientific Officer - In Vitro

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Detail information about job Scientific Officer - In Vitro. Terms and conditions vacancy

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.

Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top four cancer centres globally.

The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.

The Paediatric Solid Tumour Biology and Therapeutics Team under the leadership of Professor Louis Chesler, MD, PhD, FRCPCH, is internationally recognized and at the forefront of the field of developing novel mouse models and using molecular biology and preclinical imaging analyses to better understand childhood solid tumours. Importantly, we then specialize in using this knowledge to design and test new drug and new drug combination treatments. It is our ultimate goal to translate our preclinical findings into the paediatric clinic to increase the survival of children with cancer.

We currently have an exciting opening for an experienced Scientific Officer speciaising in in vitro techniques to provide technical expertise and support towards the team’s paediatric cancer biology project portfolio with a specific interest in investigating novel targeted mechanisms to treat drug resistant and bone marrow metastatic disease.

The successful candidate will be highly competent at undertaking IHC, protein expression analysis, IF, Western blots and RNA extraction/cDNA quantification experiments and must have demonstrable experience and a track record in molecular biology, tissue culture, lentivirus preparations and cell culture manipulation including transduction/transfection as well as other standard in vitro technologies. This is an exciting position and the successful candidate will be able to develop and enhance their skills in a critical area of childhood cancer research.

Whilst not essential it would be advantageous if the successful applicant has knowledge of or an interest in animal work and a potential willingness to assist and develop skills in the in vivo setting.

Accurate record keeping, and project management, preferably within the pre-clinical setting and a keen interest in the field of cancer research and therapeutics is highly desirable.

The appointment will be on a Fixed Term Contract for up to 2 years in first instance with substantive extensions possible dependent upon funding. The starting salary will be in the range of £21,266 - £31,602 per annum inclusive based upon relevance of skills and experience.

Informal enquiries can be made via email to Regan Barfoot ([email protected]). Please note this address is for enquiries only and you should not send your application to this email address.

To apply please upload your CV and covering letter (addressing with specific examples how you meet the person specification and incl. the names and addresses of two referees) online at http://www.icr.ac.uk/careers.

We consider all applications on merit and have a strong commitment to enhancing the diversity of our staff.