Postdoctoral Research Associate in Cell and Tissue Multiscale Modelling
Health and Medical,Anatomy, Physiology and Pathology,Physical and Environmental Sciences,Physics and Astronomy,Engineering and Technology,Mechanical Engineering,Biotechnology
Short info about job
Company: University of Sheffield
Department: Faculty of Medicine, Dentistry & Health - Department of Oncology & Metabolism
Salary: £30,688 to £38,833 per annum, Grade 7
Hours: Full Time
Contract type: Fixed-Term/Contract
Type / Role: Academic or Research
Phone: +44-1259 5091033
Fax: +44-1389 1127990
E-mail: N\A
Site: N\A
Detail information about job Postdoctoral Research Associate in Cell and Tissue Multiscale Modelling. Terms and conditions vacancy
Summary:
The Insigneo Institute for in silico Medicine is an initiative between the Faculty of Engineering and the Faculty of Medicine at the University of Sheffield and the Sheffield Teaching Hospitals Foundation Trust. Insigneo intends to realise the scientific ambition behind the Virtual Physiological Human, producing a transformational impact on healthcare. Insigneo performs cutting edge research in areas of fundamental and applied biomedical modelling, imaging and informatics. In particular, over the next five years it will focus on the Digital Patient, in Silico Clinical Trials, and Personal Health Forecasting. We intend to achieve transformational impact on healthcare through multidisciplinary collaboration in strategic areas, which initially will include personalised treatments and independent, active and healthy ageing. Our team of academics has an international and interdisciplinary profile and a strong commitment to clinical and industrial translation with impact in future healthcare. For more information on Insigneo please see our web pages: http://www.insigneo.org
MultiSim is a five-year programme that aims to create a new modelling framework for the human musculoskeletal system. The £6.7M Frontier Engineering grant from the Engineering and Physical Sciences Research Council (EPSRC) – awarded to the world leading and innovative Insigneo Institute – will improve treatments for diseases of the musculoskeletal system.
The post holder will work towards developing dynamic multi-scale bone remodelling units in the tibia responding to biomechanical stimulations under physiological and pathological conditions. A combined agent-based model (ABM) and finite element (FE) framework will be utilised to simulate signalling networks, including that of the parathyroid hormone (PTH), and monitor their influence on cell-cell interaction and emergent behaviour. The models will be integrated into a hypermodelling framework that consists of several sub-models at various scales (cell, tissue, organ, body) so that an overall musculoskeletal model can be generated.
You should hold a PhD in the Life Sciences, Engineering, Physics, or related disciplines and be familiar with modelling of cells and the musculoskeletal system. The post is full time and available for one year and will report to Dr Aban Shuaib and Dr Enrico Dall'Ara, Department of Human Metabolism, The University of Sheffield.
Fixed-term until 31 August 2018